ATG4D anticorps (AA 1-230)

N° du produit ABIN7265795

L’anticorps Lapin Polyclonal anti-ATG4D a été validé pour WB et IF. Il convient pour détecter ATG4D dans des échantillons de Humain.

Aperçu rapide pour ATG4D anticorps (AA 1-230) (ABIN7265795)

Antigène: ATG4D (Autophagy related 4D Cysteine Peptidase (ATG4D))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATG4D est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Classe de qualité: KO Validated

Détail du produit anti-ATG4D anticorps

Épitope: AA 1-230

Fonction: [KO Validated] ATG4D Rabbit pAb

Séquence: MNSVSPAAAQ YRSSSPEDAR RRPEARRPRG PRGPDPNGLG PSGASGPALG SPGAGPSEPD EVDKFKAKFL TAWNNVKYGW VVKSRTSFSK ISSIHLCGRR YRFEGEGDIQ RFQRDFVSRL WLTYRRDFPP LPGGCLTSDC GWGCMLRSGQ MMLAQGLLLH FLPRDWTWAE GMGLGPPELS GSASPSRYHG PARWMPPRWA QGAPELEQER RHRQIVSWFA DHPRAPFGLH

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human ATG4D (NP_116274.3).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur ATG4D

Antigène: ATG4D (Autophagy related 4D Cysteine Peptidase (ATG4D))

Autre désignation: ATG4D

Sujet: Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene belongs to the autophagy-related protein 4 (Atg4) family of C54 endopeptidases. Members of this family encode proteins that play a role in the biogenesis of autophagosomes, which sequester the cytosol and organelles for degradation by lysosomes. Alternative splicing results in multiple transcript variants.,ATG4D,APG4-D,APG4D,AUTL4,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Autophagy,Ubiquitin,Endocrine & Metabolism,Mitochondrial metabolism,Cardiovascular,Heart,ATGs,ATG4D

Poids moléculaire: 16kDa/52kDa

ID gène: 84971

UniProt: Q86TL0

Pathways: Autophagy